UHPLC and HPLC Products & Reviews

High performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Hypersil Duet C18/SAX Columns

Thermo Fisher Scientific

o  Separate hydrophobic and ionic compounds in a single runo  Select from two mixed mode phases, using either cation or anion exchange combined with C18o  Retention of compounds is optimized using mobile phase pH, ionic strength and percent organic Product detail: Hypersil Duet columns are an ideal choice for unknown compounds and metabolism studies, as they can separate hydrophobic and ionic compounds in a single analysis r…

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HyPURITY C8 Columns

Thermo Fisher Scientific

o  Based on ultra pure 180 Å pore size silica for analysis of small molecules to proteinso  Extensive quality control tests to ensure the ultimate in reproducibility and performanceo  Unbeatable peak shapes for all sample typeso  Select from five phases for a wide range of selectivity options Product detail:  HyPURITY C8 columns are based on the unique HyPURITY silica, designed to be essentially metal free and exceptional…

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HyPURITY C4 Columns

Thermo Fisher Scientific

o  Based on ultra pure 190 Å pore size silica for analysis of small molecules to proteinso  Extensive quality control tests to ensure the ultimate in reproducibility and performanceo  Unbeatable peak shapes for all sample typeso  Select from five phases for a wide range of selectivity options Product detail: HyPURITY C4 columns are based on the unique HyPURITY silica, designed to be essentially metal free and exceptionally…

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HyPURITY Cyano Columns

Thermo Fisher Scientific

o  Based on ultra pure 190 Å pore size silica for analysis of small molecules to proteinso  Extensive quality control tests to ensure the ultimate in reproducibility and performanceo  Unbeatable peak shapes for all sample typeso  Select from five phases for a wide range of selectivity options Product detail: HyPURITY Cyano columns are based on the unique HyPURITY silica, designed to be essentially metal free and exceptionall…

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Ace® LC/MS and Rapid Analysis Columns

Hichrom Limited

The need to reduce analysis times and increasing use of Mass Spectrometry (MS) as a detection technique has resulted in a requirement for shorter, narrower columns with higher efficiencies.  Selecting the highest quality column can be extremely critical for such challenging applications.  Column performance, lifetime and reproducibility were recently rated as the three most important factors in a Hichrom customer survey. Put…

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1260 Infinity II Multidetector GPC/SEC System

Agilent Technologies

With the 1260 Infinity II Multidetector GPC/SEC System, you can select from any combination of detection by refractive index, light scattering, and viscometry. The system delivers accurate, absolute molecular weights and sizes, and can be used to analyze a wide range of polymers, regardless of molecular weight range or solvent. Each detector has independent temperature control to ensure that high levels of precision and repro…

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Electrochemical Cell Designs for Coulochem® Detectors

ESA - A Dionex Company

Coulometric Electrochemical Cells- The Key to Enhanced Selectivity Coulochem cells are unique in their design, employing the patented ESA flow-through porous graphite electrode. These low-volume analytical cells contain two working electrodes. The high surface area of each electrode results in 100% reaction of the electroactive compound. The first (screening) electrode can be used to eliminate potentially interfering com…

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