Electrophysiology Products & Reviews

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Electrophysiology is the study of biological voltage changes, from a single ion channel through to a whole organ scale. Voltages can be measured using patch clamping, automated workstations, electrophysiology rigs or cell based assays. Specific cell lines, manipulators and microinjectors are also available for electrophysiology research.

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PatchPro Manipulation Systems

Scientifica Ltd

The PatchPro systems are fully integrated patch clamping solutions that work in conjunction with fixed stage nosepiece focussing scopes from Olympus, Zeiss, Nikon and Leica. They allow the user to control manipulators, microscope platforms, microscope focus and temperature control all from one neat, simple user console. With the versatility to freely combine numerous individual devices, the PatchPro systems will be perfect for…

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Mounting Solutions for Manipulators and Microscopes

Scientifica Ltd

Crucial for every experimental setup is a stable mounting system. The Scientifica range of slice platforms, top plates and microscope stages has been developed for researchers using upright or inverted microscopes who would like to move outside the field of view of the objective. Various configurations can achieve this in different ways, either by translating the entire microscope between fixed apparatus, or where laser inputs…

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SliceMate - Temperature Control Tissue Chamber

Scientifica Ltd

The SliceMate is a temperature controlled submerged recording chamber for biological samples; neatly housed in one compact unit. It utilizes cutting edge technology to give outstanding temperature control in a compact, easy and convenient package which replaces the clumsy, slow reacting and problematic water bath designs. A peltier element allows you to heat or cool the solution whilst a data file of the actual temperature is…

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LBM-7 Manual Manipulator

Scientifica Ltd

The LBM-7 was designed and developed in conjunction with scientists to be stable, have low drift and be easy to use. It bridges the gap between coarse manipulators and micromanipulators. Affectionately known as the Little Blue Manipulator, this device can be easily configured from left to right-handed. With seven axes of movement, four linear and three rotational, combined with micron resolution, the LBM-7 was designed to serv…

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ValveLink8.2® Pinch Valve Perfusion System

AutoMate Scientific Inc.

Perfusion System for real-time or pre-programmed liquid switching in perfusion, physiology, biophysics, electrochemistry, or general liquid-handling research applicationsIncrease reproducibility with 20 millisecond accuracyValveGuard™ technology detects bad valvesPrevent damage to your ValveLink and easily observe problem valves.Run experiments automatically - even unattendedMicroprocessor-based for accuracy and flexibilityBec…

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ThermoClamp™-1 Temperature Control System [8 Ch.]

AutoMate Scientific Inc.

* Combination inline heater plus multi-channel focal drug deliveryMaintain bath temperature and rapid drug wash-out with a high-flow bath line while quickly switching 8 preheated solutions through the Perfusion Pencil.® Steady 37°C at 5 ml/minute flow rates through both the bath line and tip. * Advanced auto-tuning temperature lockFuzzy logic PID software maintains chamber or reagent temperature to within 1°C of setpoint or be…

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SmartSquirt®8 Micro-Perfusion System

AutoMate Scientific Inc.

For programmable dispensing, microinjection, perfusion or spritzing of reproducible microliter volumes. Pulse a valve quickly for microliter delivery, or leave it on for constant perfusion. The short delivery path saves expensive reagents.• Deliver microliter volumes starting with as little as 100 microliters of precious drugsSwitch between eight solutions in milliseconds from a single tip• Minimize cross-contamination with Ba…

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BubbleStop8 60ml Syringe Heater - Pressurized

AutoMate Scientific Inc.

Bubbles in perfusion systems are caused by solution temperature changes. As solutions warm, they cannot hold as much gas, so they off-gas. This forms bubbles in perfusion tubing. It is especially true in inline heaters where the temperature rises dramatically. The best cure for bubbles is to pre-warm your solutions. AutoMate Scientific introduces the BubbleStop™ Syringe Heater with integrated temperature sensor and feedback. S…

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EasyCode® software 3.0 - PC Windows 98, 2000, XP

AutoMate Scientific Inc.

Program your AutoMate Scientific ValveBank® valve and TTL on-off sequences with a Windows 98, 2000, or XP computer using 'click-and-drag' timebars. Save and load unlimited programs to disk, print-out program listings, then download your programs into the ValveBank's memory in one simple step.Features: *Supports up to 16 channels *Open multiple experiment windows *List programs to screen or printer *Supports all ValveBank…

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ValveBank®8 controller

AutoMate Scientific Inc.

12VDC solenoid valve controller for real-time or pre-programmed liquid switching in perfusion, physiology, biophysics, electrochemistry, or general liquid-handling research applicationsIncrease reproducibility with 10 millisecond accuracyStand-alone design - no computer necessaryRun experiments automatically - even unattendedMicroprocessor-based for accuracy and flexibilityBecause they lack a microprocessor, competing valve co…

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Regulated Perfusion Reservoir Gas Bubbler - 8 channel

AutoMate Scientific Inc.

0-10 psi precision pressure regulator, gauge and bubblers for oxygenation or gas saturation of perfusion reservoirs or syringes.Can be added to any new or existing perfusion rig - from AutoMate Scientific, any third-party manufacturer, even homemade.Connect to a tank/bottle of gas (30 to 100 psi).Elegant design allows individual control of each gas line.

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Perfusion Pencil® + Removable Tip [8 chan. manifold]

AutoMate Scientific Inc.

An 8-into-1 multi-barrel manifold with male luer-lock fitting + removable tip available in 100, 250, or 360 micron internal diameter.Applications: *Single-cell and patch superfusion spritzing *Rapid (several millisecond) solution switching *Micro-liter dead volume8 micro-bore internal tubes come ready to connect to 1/16" i.d. tubing.Device is designed to mount in a micromanipulator.Materials: *Polypropylene, polyimide (ny…

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Brownlee Precision 410 - Four channel Instrumentation Amplifier

AutoMate Scientific Inc.

Brownlee's rugged yet easy-to-use amplifiers have four channels of a high gain/low noise amplification, lowpass filter and output offset control. A control knob adjusts amplifier parameters, and an alphanumeric LED readout displays values. There is a memory function for each channel. Input voltage noise is only 1.5µV rms.The Brownlee Precision Model 410 is a four-channel general purpose laboratory amplifier (one channel shown)…

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Brownlee Precision 440 - High Performance Four-channel Amplifier & Signal Conditioner

AutoMate Scientific Inc.

In addition to the Model 410 amplifier's features, the Model 440 offers an 8-pole Bessel lowpass filter, auto-zeroing, a line notch filter, highpass filter, multiple memories per channel, and a digital voltmeter on 2 channels. A wide bandwidth of over 500 kHz at all gains insures smooth recordings.The Brownlee Precision Model 440 incorporates four channels of sophisticated amplifier and filter circuitry in a friendly easy-to-u…

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Volatiles Pressure Upgrade - 4-channel

AutoMate Scientific Inc.

0-10 psi precision pressure regulator and pressurized 35ml syringe holder.For anyone who needs: * Faster liquid-switching * Steady flow rate * Microinjecting * Fine microliter delivery * Small pipette delivery Can be added to any new or existing perfusion rig - from AutoMate Scientific, any third-party manufacturer, even homemade.Connect to house air or a compressor (30 to 100 psi).Stainless steel construction i…

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Perfusion Pressure Kit - 8-ch

AutoMate Scientific Inc.

0-10 psi precision pressure regulator and pressurized syringe holder.For anyone who needs: * Faster liquid-switching * Steady flow rate * Microinjecting * Fine microliter delivery * Small pipette delivery Can be added to any new or existing perfusion rig - from AutoMate Scientific, any third-party manufacturer, even homemade.Connect to house air or a compressor (30 to 100 psi).Stainless steel construction includ…

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BubbleStop4 60ml Syringe Heater - Gravity

AutoMate Scientific Inc.

Bubbles in perfusion systems are caused by solution temperature changes. As solutions warm, they cannot hold as much gas, so they off-gas. This forms bubbles in perfusion tubing. It is especially true in inline heaters where the temperature rises dramatically. The best cure for bubbles is to pre-warm your solutions. AutoMate Scientific introduces the BubbleStop™ Syringe Heater with integrated temperature sensor and feedback. S…

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Double In Vivo Perfusion System - 4x 140ml

AutoMate Scientific Inc.

* Consistent resultsSteady gravity-fed delivery of buffer and fixative results in complete perfusion. * Easy to set up, use and cleanComplete system with everything down to the needles. Fits in standard hoods. * Fraction of the cost of a peristaltic pump and more reliable AutoMate Scientific is providing an option for the scientist who would rather do science than design a system, source parts, phone, buy, etc. Let us take the…

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In Vivo Perfusion System - 140ml

AutoMate Scientific Inc.

* Consistent resultsSteady gravity-fed delivery of buffer and fixative results in complete perfusion. * Easy to set up, use and cleanComplete system with everything down to the needles. Fits in standard hoods. * Fraction of the cost of a peristaltic pump and more reliable AutoMate Scientific is providing an option for the scientist who would rather do science than design a system, source parts, phone, buy, etc. Let us take the…

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In Vivo Perfusion System - 800ml

AutoMate Scientific Inc.

* Consistent resultsSteady gravity-fed delivery of buffer and fixative results in complete perfusion. * Easy to set up, use and cleanComplete system with everything down to the needles. Fits in standard hoods. * Fraction of the cost of a peristaltic pump and more reliable AutoMate Scientific is providing an option for the scientist who would rather do science than design a system, source parts, phone, buy, etc. Let us take the…

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