UHPLC and HPLC Products & Reviews

The EXP® Hand Tight Nano Fittings System offers hand-tight and hex head adjustable nut and ferrule compression fittings for extreme pressure connections between 1/32” stainless steel tubing and 6-40 ports.Ideal for nano-scale UHPLC and UHPLC/MS, this nut and ferrule compression fitting is rated to 20,000+ psi (1400+ bar). The patent-pending EXP® 1/32” Titanium Hybrid Ferrule combines the sealing capability of PEEK and robust n…

The EXP® Nano Fittings System offers hand-tight and hex head adjustable nut and ferrule compression fittings for extreme pressure connections between 1/32” stainless steel tubing and 6-40 ports.Ideal for nano-scale UHPLC and UHPLC/MS, this nut and ferrule compression fitting is rated to 20,000+ psi (1400+ bar). The patent-pending EXP® 1/32” Titanium Hybrid Ferrule combines the sealing capability of PEEK and robust nature of ti…

OPTI-MAX® Cartridge Check Valves are designed to offer maximum performance and ease of use. From the sharp, consistent threads on OPTI-MAX® custom housings, to the exacting standards used to match ball/seat sets in OPTI-MAX® cartridges, every aspect of design and manufacturing reflects an unavoidable fact: when it comes to reliable check valve operation, quality and precision make a big difference. OPTI-MAX® check valves offer…

OPTI-SOLV® Reservoir Filters employ a unique conical design inside the filter housing to prevent air bubbles from getting trapped and disturbing your analysis. While the availability of HPLC-grade solvents diminishes the need for pre-filtering, it is still imperative that a filtration device be installed in the reservoir. Placing a filter in the reservoir is an economical way to filter particles that may result from buffer sal…

A solid PTFE body keeps OPTI-SOLV® filter at the base of the bottle where a bottom-mounted titanium frit provides unrestricted solvent access. As always, Optimize makes installation as simple as possible - no tools or fittings required and includes 5 feet of pre-installed PTFE tubing. OPTI-SOLV Reservoir Filters employ a unique conical design inside the filter housing to prevent air bubbles from getting trapped and disturbing…

The OPTI-SOLV® Mini Filter provides low-impact filtration in a package no larger than a finger tight fitting. Use them to extend the life of your analytical column, or before your mass spectrometer as a last line of defense against debris. Perfect zero-dead-volume connections are obtained every time with our patented automatic tube stop depth adjustment. Unique depth-filtering elements allow for greater capacity with no band s…

The OPTI-SOLV® Nano Filter follows our Micro Filter but cuts the internal volume down even further. With less than 50 nL of internal volume, the OPTI-SOLV® Nano Filter is ideal for mass spectrometry to protect your electrospray and nanospray tips from clogging with debris. Like the Micro and Mini Filter, the Nano Filter is designed to be used in today's low volume, high sensitivity chromatographic applications as a last line o…

For your volume critical filtering needs, we now offer the OPTI-SOLV® Micro Filter. Based on the same design that has made the Mini Filter a huge success, the Micro Filter cuts the internal volume to less than 200 nL but retains the ease of use and functionality of the Mini Filter. The Micro Filter is designed to be used in today's low volume, high sensitivity chromatographic applications as a last line of defense against debr…

The user-friendly Hand-Tight OPTI-SOLV® In-Line Filter System is well suited for a number of applications, such as high temperature, high-pressure environments where quick changes are imperative. The unique swivel design allows frits to be changed without removing the connecting tubing. Just plumb it once and leave it. The frictional forces generated at the piston/seal interface inevitably lead to particulate shedding. Placeme…

The user-friendly Wrench-Tight OPTI-SOLV® In-Line Filter System is well suited for a number of applications, such as high temperature, high-pressure environments where quick changes are imperative. The unique swivel design allows frits to be changed without removing the connecting tubing. Just plumb it once and leave it. The frictional forces generated at the piston/seal interface inevitably lead to particulate shedding. Place…