Solid-phase extraction (SPE) is used for clean-up, extraction and concentration of semi-volatile or non-volatile analytes from complex mixtures including blood, urine and food samples. Multiple formats are available for conducting SPE, including prepacked SPE cartridges, disks and microplates, as well as SPE sorbent powders for manual packing. SPE systems can be used to automate the process and extract multiple samples at once. Solid-phase microextraction (SPME) and supported liquid extraction (SLE) products are also available in the same formats. Find the best SPE, SLE and SPME equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
The SupelMIP SPE line consist s of highly cross-linked polymers that are engineered to extract a single analyte of interest or a class of structurally related analytes with an extremely high degree of selectivity. This is possible because selectivity is introduced during MIP synthesis in which a template molecule, designed to mimic the analyte, guides the formation of specific cavities or imprints that are sterically and chemi…
Dispersive SPE (dSPE), often referred to as the "QuEChERS" method (Quick, Easy, Cheap, Effective, Rugged, and Safe), is modern sample prep technique that is becoming increasingly popular in the area of multi-residue pesticide analysis in food and agricultural products. Using the QuEChERS method, food/agricultural samples are first extracted with an aqueous miscible solvent (e.g., acetonitrile) in the presence of high amoun…
Introducing the Supel-Select SCX SPE Tube from Sigma Aldrich
Supel ™ Genie Online SPE cartridges are a sample preparation solution that offer a seamless workflow from start to finish performed entirely 'online' the LC instrument. Typically, an autosampler would take the samples from a collection plate or tubes, and inject them directly onto the SPE cartridge located on the analytical instrument (LC instrument). This enables an entirely hands free workflow which eliminates the risk o…
Supel™ Genie HybridSPE® online cartridges have been developed as an alternative to traditional 96-well plate and individual cartridge formats for phospholipid removal and sample preparation. The HybridSPE online cartridges have been designed for online phospholipid removal allowing direct injection of protein precipitated samples for LC/MS analysis. When the samples flow through the HybridSPE online traps, the phospholipids ar…
Chem Elut S products enable reproducible SLE results with high data quality and sample capacity. Consistent pore and particle sizes allow for batch-to-batch repeatability and uniform flow. Emulsions are also avoided, because there is no need for shaking. Compared to liquid-liquid extraction, Chem Elut S reduces analyst-to-analyst variability, improves matrix removal, and requires minimal extraction solvent, which leads t…
MultiVac™ Vacuum Manifolds have 3-port and 6-port options in stainless steel and aluminum. Compatible with all Rocker filter holders and mainstream disposable funnels from Sartorious, Pall, and Millipore.
MultiSEP™ solid phase extraction wells from Thermo Electron offer robust and reproducible sample preparation and pre-concentration on a routine basis.Wells are available in pre-assembled plate format or as individual wells to allow customisable plates to be assembled by the user.Sorbent packings include the ever-popular silica based bonded phases and also include novel and unique chemistries for specialised applications. Multi…
The HySphere™ cartridge range has been specially developed for the Symbiosis / Prospekt on-line SPE system. The sorbents are exclusively developed by Spark to ensure optimal efficiency and reproducability for a wide range of compounds. The most important feature is the size of the sorbent particles, which is (for most sorbents) < 10 µm as compared to 40 µm in traditional SPE tubes. The elution volume of the 8 µm cartridge is m…
Advanced Polymer Technology for Simplified SPE Bond Elut Plexa offers simple, easy-to-use methods with general purpose extraction mechanisms to simplify SPE. In addition, Plexa provides performance enhancements due to a unique polymeric architecture with a non-retentive, hydroxylated, amide-free surface and a non-polar PS/DVB core for retaining small molecules. Binding of proteins and lipids on the polymer surface is minimiz…
Polymeric Cation Exchange for Simplified SPE Bond Elut Plexa PCX is a further milestone in the development of simple and robust SP methods. Plexa PCX uses a polymeric cation exchange resin that combines the outstanding properties of Bond Elut Plexa - superior flow characteristics and improved analytical performance - with strong cation exchange functionalities. This mixed-mode SPE sorbent removed neutral and acidic interfere…
bed wt. 25 mg, volume 10 mL , (LRC), pk of 50 Application A class selective MIP phase for the multi-residue extraction of beta-agonists in urine, tissues, and other biological fluids. SupelMIP - Beta-agonists was developed for the selective extaction of a broad range o beta-agonists such as brombuterol, clenbuterol, formoterol, isoxuprine, mapenterol, ractopamine, ritrodine, salbutamol, salmeterol, terbutaline, tulobuterol, zi…
Pipette Based SPE Bond Elut OMIX pipette tips reliably purify and enrich femtomole and picomole levels of peptides and proteins prior to MALDI-TOF or LC/MS/MS. The unique monolithic sorbent technology used in Bond Elut OMIX consistently outperforms other tips by delivering uniform flow and strong analyte-to-surface interactions. Available in three formats, Bond Elut OMIX tips bind more peptides to deliver better sequence…
Commonly used for the solid phase extraction of analytes from complex sample matrices. A variety of functional groups, such as octadecyl (C18) and octyl (C8) can be bonded to the silica surface to provide non polar interactions. Each of these sorbents exhibits unique properties of retention and selectivity for a particular analyte. The choice of which sorbent is best for a particular method will be influenced by the percent…
Patent pending HybridSPE – Precipitation (HybridSPE-PPT) technology is a simple and generic sample prep platform designed for the gross level removal of endogenous protein and phospholipid interferences from biological plasma and serum prior to LC-MS or LC-MS/MS analysis. Biological plasma or serum is first subjected to protein precipitation via the addition and mixing of acidified acetonitrile. Precipitated proteins are then…
3M Bioanalytical's Empore ci8 47mm Disk - Commonly used for the solid phase extraction of analytes from complex sample matrices. A variety of functional groups, such as octadecyl (C18) and octyl (C8) can be bonded to the silica surface to provide non polar interactions. Each of these sorbents exhibits unique properties of retention and selectivity for a particular analyte. The choice of which sorbent is best for a particu…
SDB-XC is a poly(styrenedivinylbenzene) copolymer used as a reversed phase sorbent for solid phase extraction. SDB-XC is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked. It does not exhibit the secondary cationic (silanol) interactions and pH limitations common to bonded silica sorbents, so it offers more predictable and reproducible reversed phase interaction.
SDB-RPS is a poly(styrenedivinylbenzene) copolymer that has been modified with sulfonic acid groups to make it hydrophilic. SDB-RPS is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked. The sulfonation imparts unique selectivity for organic analytes that are polar in nature, such as drugs, drug metabolites, water-soluble pesticides and pesticide metabolites. SDB-RPS is also u…
Cation-SR is a poly(styrenedivinylbenzene) copolymer that has been modified with sulfonic acid. Note that Cation-SR is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked. The functional group imparts selectivity for cationic analytes, such as primary, secondary and tertiary amines.
3M Bioanalytical Anion-SR is a poly(styrenedivinylbenzene) copolymer that has been modified with quaternary ammonium groups. Note that the 3M Anion-SR is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked. The functional group imparts unique selectivity for anionic analytes, such as Endothall, Dalpon and haloacetic acids.
The Oil & Grease Disk was specifically designed for EPA Method 1664 (N-Hexane Extractable Materials (HEM) and Silica Gel Treated N-Hexane Extractable Material (SGT-HEM) by Extraction and Gravimetry). EPA Method 1664 Revision A was approved for use in the United States and published in the Federal Register on May 14, 1999. The Oil & Grease Disk incorporates C18 sorbent particles within a hydrophobic matrix. For EPA Method 166…
