Solid-Phase Extraction Products & Reviews

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Solid-phase extraction (SPE) is used for clean-up, extraction and concentration of semi-volatile or non-volatile analytes from complex mixtures including blood, urine and food samples. Multiple formats are available for conducting SPE, including prepacked SPE cartridges, disks and microplates, as well as SPE sorbent powders for manual packing. SPE systems can be used to automate the process and extract multiple samples at once. Solid-phase microextraction (SPME) and supported liquid extraction (SLE) products are also available in the same formats. Find the best SPE, SLE and SPME equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Strata-X-Drug B Plus

Phenomenex Inc

Perform your enzyme hydrolysis in a 96-well plate with Solvent Shielding Technology™ to hold solvent for 6 hours or more! •    Save Time-Eliminate transfer steps •    Save Money-Decrease consumables and solvents cost •    Simplify Your Method-No equilibration or condition required  

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Supel™Genie Online SPE Cartridges

Merck

Supel ™  Genie Online SPE cartridges are a sample preparation solution that offer a seamless workflow from start to finish performed entirely  'online' the LC instrument. Typically, an autosampler would take the samples from a collection plate or tubes, and inject them directly onto the SPE cartridge located on the analytical instrument (LC instrument). This enables an entirely hands free workflow which eliminates the risk o…

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Supel™ Genie HybridSPE® Online SPE Cartridges

Merck

Supel™ Genie HybridSPE® online cartridges have been developed as an alternative to traditional 96-well plate and individual cartridge formats for phospholipid removal and sample preparation. The HybridSPE online cartridges have been designed for online phospholipid removal allowing direct injection of protein precipitated samples for LC/MS analysis. When the samples flow through the HybridSPE online traps, the phospholipids ar…

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Enviro-Clean Fusion®Ag+

UCT, Inc.

Simple and Accurate Fractionation for EPH Testing with New Silver Functionalized Enviro-Clean Fusion®Ag+ This novel sorbent is designed to help overcome the challenges associated with traditional silica gel fractionation. Featuring silver ions anchored onto a solid support, this chemistry provides enhanced selectivity, capacity, and overall performance.

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Enviro-Clean DVB – PE Frits 500mg 6mL

UCT, Inc.

UCT's Enviro-Clean® Polymeric WAX Cartridges w/Polyethylene frits have been successfully utilized for the extraction of 26 diverse per- and polyfluoroalkyl substances (PFASs) in drinking water in addition to the 14 covered in the US EPA Method 537.  

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96 Well Plates and Wells From Thermo Electron

Thermo Fisher Scientific

MultiSEP™ solid phase extraction wells from Thermo Electron offer robust and reproducible sample preparation and pre-concentration on a routine basis.Wells are available in pre-assembled plate format or as individual wells to allow customisable plates to be assembled by the user.Sorbent packings include the ever-popular silica based bonded phases and also include novel and unique chemistries for specialised applications. Multi…

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Hysphere Range of SPE Cartridges

Spark System Solutions B.V.

The HySphere™ cartridge range has been specially developed for the Symbiosis / Prospekt on-line SPE system. The sorbents are exclusively developed by Spark to ensure optimal efficiency and reproducability for a wide range of compounds. The most important feature is the size of the sorbent particles, which is (for most sorbents) < 10 µm as compared to 40 µm in traditional SPE tubes. The elution volume of the 8 µm cartridge is m…

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SupelMIP™ SPE - Beta-agonists

Sigma-Aldrich Supelco

bed wt. 25 mg, volume 10 mL , (LRC), pk of 50 Application A class selective MIP phase for the multi-residue extraction of beta-agonists in urine, tissues, and other biological fluids. SupelMIP - Beta-agonists was developed for the selective extaction of a broad range o beta-agonists such as brombuterol, clenbuterol, formoterol, isoxuprine, mapenterol, ractopamine, ritrodine, salbutamol, salmeterol, terbutaline, tulobuterol, zi…

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3M™ Empore™ C8 47 mm Disk

3M Bioanalytical

Commonly used for the solid phase extraction of analytes from complex sample matrices.  A variety of functional groups, such as octadecyl (C18) and octyl (C8) can be bonded to the silica surface to provide non polar interactions.  Each of these sorbents exhibits unique properties of retention and selectivity for a particular analyte.  The choice of which sorbent is best for a particular method will be influenced by the percent…

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PoraPak Rxn

Waters

Waters offers PoraPak™ Rxn, a family of polymer-based chromatography products for superior cleanup of synthetic reactions. PoraPak Rxn products are available in two chemistries: PoraPak Rxn CX, a strong cation-exchange sorbent and PoraPak Rxn RP, a reversed-phase sorbent.PoraPak Rxn sorbents are based on copolymers that exhibit the following properties:Hard material that does not develop increasing back pressure with flowLitt…

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HybridSPE®-Precipitation, 96-well Plate, pk of 1

Sigma-Aldrich Supelco

Patent pending HybridSPE – Precipitation (HybridSPE-PPT) technology is a simple and generic sample prep platform designed for the gross level removal of endogenous protein and phospholipid interferences from biological plasma and serum prior to LC-MS or LC-MS/MS analysis. Biological plasma or serum is first subjected to protein precipitation via the addition and mixing of acidified acetonitrile. Precipitated proteins are then…

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  • Best New Separations Product of the Year

3M™ Empore™ C18 47 mm Disk

3M Bioanalytical

3M Bioanalytical's Empore ci8 47mm Disk - Commonly used for the solid phase extraction of analytes from complex sample matrices.  A variety of functional groups, such as octadecyl (C18) and octyl (C8) can be bonded to the silica surface to provide non polar interactions.  Each of these sorbents exhibits unique properties of retention and selectivity for a particular analyte.  The choice of which sorbent is best for a particu…

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3M™ Empore™ SDB-XC 47 mm Disk

3M Bioanalytical

SDB-XC is a poly(styrenedivinylbenzene) copolymer used as a reversed phase sorbent for solid phase extraction.  SDB-XC is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked.  It does not exhibit the secondary cationic (silanol) interactions and pH limitations common to bonded silica sorbents, so it offers more predictable and reproducible reversed phase interaction.

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3M™ Empore™ SDB-RPS 47 mm Disk

3M Bioanalytical

SDB-RPS is a poly(styrenedivinylbenzene) copolymer that has been modified with sulfonic acid groups to make it hydrophilic.  SDB-RPS is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked.  The sulfonation imparts unique selectivity for organic analytes that are polar in nature, such as drugs, drug metabolites, water-soluble pesticides and pesticide metabolites.  SDB-RPS is also u…

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3M™ Empore™ Cation Exchange-SR 47 mm Disk

3M Bioanalytical

Cation-SR is a poly(styrenedivinylbenzene) copolymer that has been modified with sulfonic acid.  Note that Cation-SR is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked.  The functional group imparts selectivity for cationic analytes, such as primary, secondary and tertiary amines.

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3M™ Empore™ Anion Exchange-SR 47 mm Disk

3M Bioanalytical

3M Bioanalytical Anion-SR is a poly(styrenedivinylbenzene) copolymer that has been modified with quaternary ammonium groups.  Note that the 3M Anion-SR is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked.  The functional group imparts unique selectivity for anionic analytes, such as Endothall, Dalpon and haloacetic acids.

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3M™ Empore™ Oil & Grease 47 mm Disk

3M Bioanalytical

The Oil & Grease Disk was specifically designed for EPA Method 1664 (N-Hexane Extractable Materials (HEM) and Silica Gel Treated N-Hexane Extractable Material (SGT-HEM) by Extraction and Gravimetry).  EPA Method 1664 Revision A was approved for use in the United States and published in the Federal Register on May 14, 1999.  The Oil & Grease Disk incorporates C18 sorbent particles within a hydrophobic matrix. For EPA Method 166…

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3M™ Empore™ Chelating 47 mm Disk

3M Bioanalytical

Empore™ Chelating Disks provide a way to selectively remove multivalent metal cations from solutions.  This selectivity can be used to concentrate metals from a sample for analysis or to isolate and remove metal interferences from a complex organic or inorganic sample matrix.  In the latter case, the purified filtrate is ready for use.  The chelating disk has an affinity for multivalent (primarily 2+ and 3+) transition element…

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3M™ Empore™ Carbon 47 mm Disk

3M Bioanalytical

Empore Carbon Disks are designed for the extraction of volatile, highly polar, and water soluble compounds from aqueous solutions.  The Empore Carbon Disk provides all the advantages of activated carbon in a compact and thin Empore Disk.

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