A comparison of HRAM Orbitrap and MS/MS for anaylsis of polyfluoroalkyl substances by EPA Method 537

In this application note, Thermo Fisher Scientific demonstrates liquid chromatography - high-resolution, accurate-mass (LC-HRAM) methodology using Orbitrap™ technology as a sensitive, accurate and reliable quantitative alternative to the use of triple quadruple mass spectrometers, while stimultaneously determining unknown perfluorinated compounds in the same drinking water extracts.