A Rapid and Sensitive Method Estimation of Octreotide in Human Plasma Using UPLC and Xevo TQ-S

A unique optimization of a Waters system for bioanalysis, from sample preparation to UPLC chromatography to tandem quadrupole MS, enables the determination and quantification of octreotide, a cyclic octapeptide that is used for treating cancer patients, at the 5 pg/mL level.