Analysis of FFPE Treated Clinical Tissue Sections Obtained from Human Intraocular Malignancy, Uveal Melanoma by Mass Spectrometry Imaging (MSI)

This poster describes clinical research into FFPE tissue sections obtained from the human intraocular disease Uveal Melanoma (UM), which remains the most common intraocular malignancy in adults. Mass spectrometry (MS) imaging allows the investigation of the spatial distribution of molecules at complex surfaces. The combination of molecular identification and location provides a chemical microscope that can be used for the direct biomolecular characterization of histological tissue surfaces. MS based imaging allows label-free detection and mapping of a wide-range of biological compounds whose presence or absence can be the direct result of disease pathology.