Application of the Bioruptor® Pico for Shearing Chromatin Fragments for ChIP-seq from Human Tumor Tissue

Application of the Bioruptor® Pico for Shearing Chromatin Fragments for CHiP-seq From Human Tumor TissueApplication of the Bioruptor® Pico for Shearing Chromatin Fragments for ChIP-seq From Human Tumor Tissue

2 Apr 2017

This application note illustrates how the Bioruptor® Pico (Diagenode) can process various human tumor tissues for ChIP-seq analyses of transcription factors as well as epigenetic marks. Chromatin must be optimally sheared prior to immunoprecipitation and subsequent library preparation for Illumina sequencing.

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