Assessing Aggregation and Kinetics of Liposome-Protein Complexes using NanoSight Technology

This whitepaper describes rapid characterization of liposome-insulin receptor complexes by Nanoparticle Tracking Analysis using the NanoSight NS300 from Malvern Instruments. The NanoSight technology observes the Brownian motion of particles in suspension and calculates their size through the Stokes-Einstein equation. The paper concludes that the high resolution NTA using the NanoSight NS300 is a useful technique in analyzing the aggregation kinetics of liposome preparations.