Nanosight Pro
Characterizing Nano- and Biomaterials has never been so quick, easy, and accurate.
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Works well for sizing and quantifying LNPs and adenovirus
LNP and Adenovirus characterization
I've been using the Nanosight Pro for several months now to characterize LNPs and adenovirus both around 100 nm. Overall, my experience has been positive. There are definitely some challenges that come up and require experience. I've contacted support multiple times which have been good experiences. Pros: works great for quantifying and sizing my particles. Results can be reproducible. The video is useful and allowed us to see some unusual aggregate chains. Running samples is straight forward. Cons: Running samples can be problematic if unaware of potential problems. Air bubbles are the biggest problem. These can be very difficult to remove sometimes and must be checked for after loading a sample. Thorough washing between samples can be required depending on the sample. The fluorescence capability is nice but so far particle brightness seems lacking. Particle bleaching was also observed. You can reverse the flow to reduce bleaching but I have not tried it. Other thoughts: I have found some LNPs require washing with detergent after a few samples because (I suspect) lipids are sticking to the plastic and degrading the image sharpness. The concentration (particles/ml) also needs to be optimized for your sample to get an accurate count and minimize carryover between samples.
Review Date: 9 Oct 2024 | Malvern Panalytical
Rapid running with the easy method, and show great results!
Analyze the nanoscale materials, e.g. lipid-based nanoparticles.
The software is not complicated; it saves time for training the new users and running the experiments. It has autofocus and a camera that is easy and convenient. Also, the data was precise and accurate.
Review Date: 7 Nov 2023 | Malvern Panalytical
Great results, this will provide valuable data for many investigators
Analyze extracellular vesicles
We purchased this instrument for our core laboratory. It will be utilized by several investigators for viral and extracellular vesicle research. There is not another instrument on campus that would provide the data that this does. It is easy to use and importantly automate for walk away use. The training was outstanding and the instrument is easy to care for.
Review Date: 17 Mar 2023 | Malvern Panalytical
Great
analyze the size of nanoparticle and exosome
It is quite easy to use and the results are reliable. We will purchase the product of Malvern Panalytical again in the future.
Review Date: 13 Feb 2023 | Malvern Panalytical
Manufacturer's Response
It’s great to hear you are happy with Malvern Panalytical product and that NanoSight NS300 is providing you with the data you can rely on.
Rapid analysis
Rapid analysis of nano particles
The Malvern Panalytical NanoSight NS300 Instrument provides an easy-to-use, reproducible platform for nanoparticle characterization. Allows rapid analysis of all types of nanoparticles from 0.01 - 1 µm* in diameter, depending on the instrument configuration and sample type.
Review Date: 22 Jul 2022 | Malvern Panalytical
Very effective and precise results.
Nanomaterial Characterization
This is an awesome product by Malvarn International. Easy to use, compatible and reliable product for Scientific research.
Review Date: 10 Jun 2022 | Malvern Panalytical
It is essential to check the size and particle number concentration of exosomes.
Check the concentration of Exosome, Check the size of the protein particles.
It is essential to check the size and particle number concentration of exosomes. We can check if exosome is separated well. The analysis method is also simple, making it easy to use equipment. There is no need for consumption materials, so the maintenance cost is low.
Review Date: 16 Dec 2021 | Malvern Panalytical
Manufacturer's Response
Thank you for positive feedback, it’s great to hear that NanoSight NS300 is not only simple and easy to use system but also, it’s essential tool in exosomes characterization.
Amazing technology with ease to handle.
Nanofluids
This patented technology is indeed helpful while dealing with the nanofluids research domain. The precision and the sensitivity provide accuracy to the data which is highly opted for the extensive research at the nanoscale. The artistic way of visualising the nanofluid's properties is really an add-on to the research.
Review Date: 15 Dec 2021 | Malvern Panalytical
Manufacturer's Response
Thank you for the great review of the NanoSight NS300 system Kalyani. It’s good to hear that you’ve had a positive experience with the instrument. We love your phrase of “artistic nanofluids visualisation” and your appreciation to the high-quality data is a music to our ears. Thank you!
Great reliable instrument.
Extracellular vesicle characterization
The NS300 is a great instrument and is undoubtedly the industry gold standard for exosome characterization. Simple to use and reliable results.
Review Date: 12 Mar 2021 | Malvern Panalytical
Manufacturer's Response
Thank you for positive feedback Rob, it’s good to hear you enjoy working with NanoSight NS300.
Great product, reproducible data and consistent performance.
Research interest
NanoSight NS300 provides easy-to-use, manageable and reproducible data in the long term. It can be easily used for mono vs. polydisperse sample matrices with adjustable parameters. It is not compound specific, so it can easily be modified for solid particles, bubbles and many kinds of liquids. With rapid analysis; size and concentration of particles will be monitored easily. Also, when problems occured, the company has been very helpful. They are contacting us in a day and they are always providing different approaches and solution. Therefore, I suggest this product for all users that need to measure accurate particle size, concentration and distribution analysis.
Review Date: 12 Mar 2021 | Malvern Panalytical
Manufacturer's Response
Thank you for the great review of the NanoSight NS300 Meryem. We are glad to hear that you’ve had a positive experience with the instrument and our support team.
With the introduction of the NanoSight Pro, Malvern Panalytical provides the best in class, simple and rapid NTA solution for nano- and biomaterials characterization.
The combination of advanced engineering and a blend of smart features assures NTA measurements are efficient, quick, and accessible to all users. Powered by machine learning, NS Xplorer software enables automated measurements, removes subjectivity, and provides the highest quality size and concentration data for both, the light scatter and fluorescence analysis.
Interchangeable lasers allow application flexibility, whilst Smart Manager connection assures robustness without a worry for quality issues or downtime.
Features
- Quick install & analysis: NanoSight Pro can be used by every user in every lab. Smart installation allows you to get up and running quickly. With minimum setup, easy operation and intuitive NS Xplorer software you can measure your samples in minutes.
- Intelligent & automated: Powered by machine learning and intelligent features, NanoSight Pro automates processing and eliminates human error, delivering superior particle identification and precise particle tracking for the highest quality and reproducible data.
- Highest resolution: The NanoSight Pro measures nanoscale particles in the range of 10 nm - 1000 nm including low scattering and biological particles. Particle–by–particle analysis assures high resolution size and concentration data with visual confirmation.
- Power of fluorescence: In addition to light scatter, fluorescence signals can be detected from fluorescently tagged biologics or synthetic particles providing even greater insight into your sample. Interchangeable laser modules with the choice of four excitation wavelengths can be used along with the matching long pass filters for the optimum setup supported by analysis in flow for better sampling and tracking of even photobleaching samples.
