Characterization of Antibodies and Antibody Drug Conjugates by a Novel High Resolution Quadrupole Time-of-Flight Mass Spectrometer

This poster demonstrates how continued development in analytical technologies and informatics for biological molecules have permitted more accurate characterization of drug to antibody ratio (DAR), drug distribution and identification of conjugation sites. These improved tools for characterization of antibodies and immuno-conjugates aid in the development of antibody drug conjugates (ADCs), an exciting new class of cancer therapeutics