Characterization of Critical Reagents for Ligand Binding Assays

Ligand binding assays are utilized throughout the large molecule drug development process. However, their robustness, accuracy and reproducibility depend on the quality of critical reagents. The unique characteristics of these reagents are crucial to assay performance, and require careful characterization. To ensure their consistent characterization in bioanalytical laboratories, in this application note a team of pharmaceutical scientists outline recommendations and best practices for this process, particularly during the early stages of drug development.