Chemical Characterization of Pharmaceutical Samples by Confocal Raman Microscopy and Correlative Techniques

In pharmaceutical research, confocal Raman microscopy (CRM) can be used to probe the distribution of chemical components within formulations, characterize the homogeneity of pharmaceutical samples and to characterize contaminants and foreign particulates. This application note details a study which demonstrates how CRM can be beneficially applied in the pharmaceutical field. It concludes that combining CRM with other techniques – such as topographic Raman imaging and AFM – expands its analyzing capabilities, giving a comprehensive understanding of a pharmaceutical product.