Chromatrap® ChIP-seq from Native and Cross-Linked Chromatin

This application note provides a detailed genome wide comparison of native and cross-linked chromatin immunoprecipitation followed by next generation sequencing (ChIP-seq) using the patented solid state Chromatrap® spin column technology. Chromatrap® extraction and capture technology is used for both native and cross-linked chromatin preparation methods. High quality FASTQC metrics and significant genome wide peak enrichment levels are obtained using both assay technologies