Desalting Samples with RediSep Rf Gold® C18Aq Columns

Compounds are often purified with solvents that contain salts or buffers that need to be removed prior to subsequent studies with the compound. The RediSep Rf Gold® C18Aq columns have the ability to adsorb compounds under highly aqueous conditions and are ideal for removing the salt from a sample. The method described also removes a large portion of water from samples dissolved in aqueous solvents facilitating evaporation. The procedure is similar to solid phase extraction, but on a larger prep scale.