Detection of DENARASE® Endonuclease with the Benzonase® ELISA Kit II

Endonucleases originating from Serratia marcescens are regularly used in the purification processes of biological molecules to digest DNA originating from the host cells. Benzonase® ELISA Kit II is used to quantify trace amounts of endonucleases expressed in E. coli. This application note shows that trace amounts of both endonucleases expressed in E. coli and Bacillus sp. can be detected with the Benzonase® ELISA Kit II.