Evaluation of the ambr® 250 Fully Automated Single-use Bioreactor System For High Throughput Fed-Batch Culture

Fed-batch culture is the commonly adopted biologicals manufacturing method used in many biopharmaceutical companies as it can generate gram/litre amounts of protein-based therapeutics. However, to obtain the maximum production of therapeutic proteins requires the optimum formulation of culture media and feeds, as well as the correct bioprocess parameters. This application note demonstrates the use of the ambr 250 mini bioreactor system to rapidly evaluate these bioprocess conditions to support efficient fed-batch culture.