Expression of Oxidative Stress Genes in Human Stem Cells in Physiological Versus Atmospheric Oxygen Levels

Oxidative stress plays a role in the development as well as the degeneration of the brain. Oxygen levels in the developing embryo are low and proper regulation of oxygen levels is crucial for stem cells, neural progenitor cells and neurons. This poster investigates the role of oxidative stress in human induced pluripotent stem cells (iPS cells) by testing expression of several genes involved in the cellular oxidative stress response when cells were maintained in different oxygen concentrations.