From QC to quantitation: Utility of QReSS metabolites in FBS measurements

Metabolomics is a rapidly growing field of research that has unique and proven advantages in systems biology and biomarker discovery. Great advances have been made over the past decade on the feasibility of mass spectrometry (MS)-based metabolomics. Despite the advancements, there remains a pervasive need for quality control (QC) as metabolomic experiments can experience unwanted variations that threaten the quality of the acquired data. The use of reliable QC measures is therefore critical to assess and prevent unwanted preanalytical and instrumental variation.

In this application note, the QReSS™ standard mixes (CIL cat no. MSK-QReSS1 and MSK-QReSS2) were used in the QC of metabolites from variably sourced FBS samples.