Functional analysis of PHLDA3, a target gene for the tumor suppressor gene p53

In this application note, discover more about the use of Beckman Coulter Life Sciences AMPure XP DNA clean-up process in the research of targeting p53. Beckman interviews Dr. Reiko Ohki, Head of Fundamental Oncology, National Center, Tokyo, who works on p53, its downstream factors and its role in tumorigenesis. She discussed the importance of the DNA clean-up process in the analysis of mutations in PHLDA3 genes in cancer tissues she is analyzing.