Genetic and epigenetic study of formalin-damaged DNA with duet multiomics solution evoC 6-base sequencing

This study explores the impact of formalin fixation on DNA methylation profiles using the innovative 6-base sequencing technology, duet multiomics solution evoC. By analyzing formalin-compromised, FFPE, and fresh-frozen cancer samples, the research demonstrates that despite minor predictable changes, the method provides reliable genetic and epigenetic insights, preserving the biological integrity of stored samples.