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duet multiomics solution evoC

Your single solution for multiomics data - Uncover a true 6-base genome for unprecedented insights into current and future biological states. Access all four canonical bases and distinguish 5‑methylcytosine (5mC) and 5‑hydroxymethylcytosine (5hmC) from a single 5ng DNA sample, in a single experiment, with high accuracy.

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duet multiomics solution evoC is comprised of a pre-sequencing workflow requiring as little as 10ng gDNA or 5ng cfDNA that seamlessly integrates with NGS sequencing platforms and a post-sequencing software package to accelerate data analysis. The post-sequencing software trims, aligns, and annotates to generate analysis-ready BAM, VCF, BedMethyl, and ASM files. Additional plugins include proprietary analysis software that facilitates analysis of multimodal data at scale.

The 6-base genome provides a combined genome and methylome with full discrimination of 5mC and 5hmC for genetic sequence analysis, variant identification, and DNA methylation analysis.

The 6-base genome data delivers:

  • Somatic vs. germline mutations
  • Variant associated methylation
  • Fragment profiles
    Methylation status of control elements
  • Differentially methylated loci and regions

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