High Sensitivity and Specificity Prediction of Drug-Induced Liver Injury Using High-Content Cell-Based Imaging

In this application note an automated cell based high content imaging assay is used for early and accurate prediction of drug-induced hepatotoxicity. Cells of hepatic origin were treated with a panel of compounds, labeled with specific fluorescent probes and automatically imaged and quantitatively analysed using the Thermo Scientific ToxInsight IVT platform.