In Vivo Imaging of a Cy5.5 Labeled Amyloid-β, an Alzheimer's Disease Associated Protein

In this application note the iBox^® Explorer™2 Imaging Microscope from UVP, LLC) is used to visualize amyloid-β peptide (Aβ) trafficking in vivo with injected Cy5.5-labeled Aβ. Overproduction of amyloid-β peptide (Aβ) and clearance mechanism failures are thought to be the cause of Alzheimer’s Disease, therefore understanding their interactions is vital for research.