Inhibition of MicroRNA Sensitizes 3D Breast Cancer Microtissues to Radiation Therapy

Dr. Nataša Anastasov leads the Personalized Radiation Therapy Group within the Institute of Radiation Biology at the Helmholtz Center Munich. This case study describes an investigation into the radiosensitizing potential of miR-21 down-regulation, using T47D breast cancer cells and T47D 3D breast cancer microtissues. The techniques and methods described here were developed using technology from InSphero and PerkinElmer.