Innovations in Cell Culture Assists Predictive Value of Liver Toxicity Assays

This application note by reinnervate Ltd shows how liver cells grown in alvetex® display significantly higher viability in comparison to cells grown in 2D culture, forming complex 3-dimensional structures much more representative of the natural in vivo environment. In addition, liver cells grown in alvetex® demonstrate increased expression of key liver enzymes and significantly enhanced metabolic activity in responses to model toxicants.