Comprehensive isotope ratio analysis of amino acids using Orbitrap Exploris Isotope Solutions

5 Jun 2025

This technical note highlights the use of Thermo Scientific Orbitrap ExplorisIsotope Solutions for precise isotope ratio analysis of amino acids, focusing on glutamic acid as a model compound. Glutamate plays a key role in metabolism, neurotransmission, and nitrogen excretion. The advanced Orbitrap technology enables simultaneous carbon, nitrogen, oxygen, and hydrogen isotope ratio analysis from intact molecular ions by a single analysis, offering valuable insights into biochemical processes and metabolic pathways.

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