Lab ultrafiltration tips and tricks

The use of ultrafiltration membranes for concentration and purificationof proteins and DNA is ubiquitous in biological laboratories. Filter devices with ultrafiltration membranes can also be used for concentration of other macromolecules such as inorganic polymers, nanoparticles or even viruses. Although performing sample concentration and buffer exchange using an ultrafiltration device is relatively simple, some tricks of the trade can improve your recovery or speed up your work flow considerably.