Lipid Imaging from Mouse Brains Using LAESI-MS and MALDI-MS Imaging

In this application note, cryosectioned mouse brain sections were comparatively analyzed by the LAESI DP-1000 and a third party vendor MALDI using parallel imaging mass spectrometry methods. The results achieved with imaging produced several characteristic mass spectral fingerprints for mouse brain tissue. In addition to various lipids, many metabolites and other biomolecules were detected and putatively identified using high mass accuracy.