Low Light Imaging of Reactive Oxidative Species (ROS) at Wound Sites Using Luminol

This application note describes the in vivo use of luminol to monitor the generation of ROS, specifically due to the inflammatory response mounted by phagocytic cells. The iBox® Scientia™ Small animal Imaging System was used for real-time imaging of ROS generation by inflammatory cells. Results demonstrate the iBox Scientia to be a powerful tool for imaging disease processes within an in vivo model.