Meeting Regulatory Requirements for Vent Filtration on Water For Injection (WFI) Tanks

Water systems for the production, storage and distribution of purified water or WFI remain critical points in pharmaceutical production plants. A key concern of regulatory authorities is the installed vent filter on high purity water-holding tanks. This document provides Pall’s technical recommendations to meet current regulatory requirements and to ensure sterile protection of the tank utilizing Emflon® HTPFR or PFR vent filters, built-in drainage utilizing Pall Advanta™ liquid and gas filter housings, prevention of condensate utilizing Pall Advanta housing trace heaters and reliable water intrusion testing utilizing the Palltronic® AquaWIT filter integrity test system.