Multiple Simultaneous Measurements Provide Improved Characterization of Protein Stability

In this application note, Unchained Labs reveals the importance of using multiple parameters to assess and optimize the stability of proteins. By using the UNit to collect fluorescence spectroscopy and static light scattering data from samples of α-chemotrypsinogen, Unchained Labs illustrates striking differences in the conformational and colloidal stability of formulations, thus demonstrating the need for multiplex analyses.