Nuclease-free water at your fingertips

Nuclease-free glassware and reagents are required for many molecular biology applications. Chemical treatment with diethylpyrocarbonate (DEPC) has long been a common practice to generate nuclease-free water, but this method has several drawbacks.

In this application note, Merck describes how an ultrafiltration cartridge can be placed at the outlet of a water purification system to deliver nuclease-free ultrapure water that can directly be used for experiments.