Octet AAVX biosensors for rapid and direct quantitation of AAV capsids

In this application note, Sartorius introduces the Octet® Bio-Layer Interferometry (BLI) platform and the Octet® AAVX Biosensor quantitation assay workflow for the rapid, real-time, and high-throughput measurement of adeno-associated virus (AAV) concentration in the bioprocess workflow. AAVX Biosensors offer a wide quantitation dynamic range, high precision, and can quantitate 10 different AAV serotypes. They are compatible with diverse sample matrices, require minimal preparation, and can be regenerated and reused up to 20 times, reducing costs. This technology provides a time-saving, labor-efficient, and less variable alternative to current methods for quantitating virus capsid concentration in AAV production and manufacturing.