Optimizing DNA extraction from blood using prepGEM™ and forensicGEM™ Blood kits

In general, DNA does not need extensive purification for the polymerase chain reaction (PCR). The key to simplifying nucleic acid preparation is to develop procedures that minimize labour and cost, but are sufficiently rigorous to remove inhibitory substances. Blood is notoriously difficult to work with because it contains nu¬merous inhibitors. This application note presents two methods for DNA extraction from blood using the prepGEM™ and forensicGEM™ Blood kits.