Pharmaceutical Formulations as 7mm and 13mm KBr Pellet Preparations for Comparison

IR spectroscopy is a useful tool for group chemical species identification of a wide variety of sample materials, particularly for the classification of “organic” chemical materials based upon carbon atoms being present in the molecular structure. A classic sampling technique for the study of solid sample types by IR transmission spectroscopy is to prepare the solid sample as a potassium bromide (KBr) disc or pellet to mount appropriately and correctly within the sampling area of an infrared spectrometer. This application note shows how a few examples of pharmaceutical formulations as tablets/pills and capsules can be prepared to form both 7mm and 13mm KBr sample pellets produced for comparison.