Pharmacological comparisons of mitragynine, 7-hydroxymitragyine, and mitragynine pseudoindoxyl

Mitragynine (MG) is the most abundant alkaloid in kratom, which has historically been used as a medication to alleviate pain. In this poster presented at the SelectScience Neuroscience Summit 2021, Jane Hufnagel et al., University of Florida, compare the pharmacodynamics of MG metabolites, 7-Hydroxymitragyine, and pseudoindoxyl. Download now for an insight into their actions at the μ-opioid receptor (MOR) and contributions to the MOR activity of MG.