Pitched-Blade vs. Spin Filter vs. Packed-bed Basket: CHO Cell Culture Comparison

In this application note, the pitched-blade impeller, the spin filter impeller and the packed-bed basket impeller are discussed, highlighting the uses and advantages for each type. Examples of actual CHO cell cultures are given for each impeller type; showing the perfusion capability when using the spin filter or packedbed basket impeller and the resulting higher cell densities over the pitched-blade impeller.