Protein post-translational modifications: Translating diversity to discovery

Following synthesis, the majority of proteins will experience modifications. Over 200 different post-translational modifications (PTMs) have been identified, with the most widely researched being phosphorylation, glycosylation, acetylation, methylation, nitrosylation, acylation, and ubiquitylation. Identifying and understanding these significant mechanisms is critical to the study of basic cell biology as well as in disease pathogenesis. In this whitepaper, RayBiotech presents the detection methods and techniques of protein PTMs, highlighting their significant role in cellular processes and disease pathways. RayBiotech explains how its PTM detection kits can be beneficial for the development of innovative therapeutic interventions. Its suite of PTM profiling tools includes easy-to-use antibody arrays to screen up to 8,000 target proteins for acetylation, palmitoylation, oxidation, glycosylation, or phosphorylation signatures.