Purification and Evaluation of Total RNA from Porcine Skin on the Bead Ruptor Elite Bead Mill Homogenizer

Hard samples such as skin and bone present a significant challenge for the extraction of RNA. Common methods require freezing the tissue, but this is typically very involved and time-consuming. This application note evaluates the potential for the extraction of RNA from porcine skin using the Bead Ruptor 24 Elite bead mill homogenizer. It was found that the Bead Ruptor 24 Elite was excellent at processing skin samples and that total RNA extracted was in excess of 600 ng/µl.