Quantitation of 22 fentanyl analog compounds with a TSQ Altis MD mass spectrometer

The rise in not only the abuse of prescription drugs, but also synthetic opioids, has created a demand for toxicology labs to test for fentanyl-related compounds, including fentanyl. In this application note from Thermo Fisher Scientific, explore a method for quantitation of the Traceable Opioid Material™ (TOM) kit compounds in urine that includes sample preparation by supported liquid extraction (SLE) and quantitation by selected reaction monitoring (SRM) on a Thermo Scientific™ TSQ Altis™ MD Triple Quadrupole mass spectrometer.