Rapid Analysis of Cells with the LAESI DP-1000 System

This application note demonstrates how the LAESI DP-1000 can be used to evaluate metabolite biomarkers in cultured cells resulting from growth conditions. This is critical to understanding the increased resistance to chemotherapy by cell lines. Spectra acquired from varying conditions of the human Pre-B cell leukemia cell line, REH were compared using Waters Markerlynx™ PCA and OPLS-DA statistical analysis.