Rapid and reproducible parallel processing of charge heterogeneity analysis of protein therapeutics by multi-capillary isoelectric focusing

5 Nov 2021

In this application note, a parallel capillary isoelectric focusing analysis using the BioPhase 8800 system and a multi-capillary separation approach is described. Protein therapeutic charge variant assessment is essential at different manufacturing stages as they are subjected to instability, causing alterations in their primary amino acid sequence.

Links

Tags