Rapid assessment of critical quality attributes with Octet BLI systems

In this application note, Sartorius discusses the importance of measuring critical quality attributes (CQAs) for ensuring desired product quality. CQAs encompass physical, chemical, biological, and microbiological properties that must be within appropriate limits. These attributes include product-specific characteristics and process-related impurities. Traditional methods such as UV spectroscopy, ELISAs, and HPLC are time-consuming and labor-intensive. The Octet^® Bio-Layer Interferometry (BLI) platform offers a fast, automated, and label-free alternative for measuring CQAs.