Routine pesticide screening solution: Data independent acquisition with a new LC/Q-TOF and dedicated screening software

The requirement for robust and reliable screening methods for pesticides in food matrices continues to emerge as a point of challenge and necessity. The utilization of data independent acquisition (DIA) affords scientists the ability to screen for targets while also acquiring non-targeted fragment information, which could be used for retroactive analysis of emerging contaminants and future suspects. A high-resolution LC/Q-TOF (quadrupole time of flight) facilitates the DIA acquisition while aiding identification with extended dynamic range, stable accurate mass, isotopic fidelity, and acquisition speeds supporting specificity of fragment ions. Agilent Technologies presents a workflow for pesticide screening that includes QuEChERs sample preparation, the Agilent 1290 Infinity II LC, the new Revident LC/Q-TOF, and MassHunter Quantitative Analysis 12 Screener Tool for fast and routine pesticide analysis.