Simultaneous detection of respiratory infectious diseases using immunoprecipitation and liquid chromatography-tandem mass spectrometry

With recent emergences of new infectious diseases and their variants, there is a need to develop a faster and more accurate analytical tool to detect different respiratory infectious disease viral agents such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza viruses. This application note from Thermo Fisher Scientific describes a targeted approach for the simultaneous detection of different respiratory infectious disease viruses using immunoprecipitation and selected reaction monitoring (SRM). The types of respiratory infectious disease viruses monitored in this note include SARS-CoV-2, influenza A and B viruses, respiratory syncytial virus (RSV), and human coronavirus (HCoV-229E).