Validation and pharmacological utility of real-time, live-cell assays for single 3D spheroids

A growing body of evidence suggests that more relevant and translational observations can be made using 3D micro-tissues and organoids as compared to 2D monolayer cell models.

In this application note, Sartorius describe methods and validation for miniaturized (96/384-well) Incucyte^® Single Spheroid Assays based on non-invasive bright-field image analysis, performed with the Incucyte^® Spheroid Analysis Software Module.