Validation of Gene Expression Markers in scRNA-Seq Using scATAC-Seq

Studying gene expression at a single-cell level can provide crucial insight into how individual cells contribute to biology and disease. Single-cell assay for transposase-accessible chromatin using sequencing (scATAC-Seq) is a powerful tool to examine gene expression regulation. Here, scATAC-Seq is used as an orthogonal approach to validate scRNA-Seq data to detect cell type population in adult mouse brain tissue.