Novel Droplet Digital PCR Assays to Detect and Quantify Somatic Mutations in Cancer Tissues and Cell-Free DNA

Dr Miguel Alcaide, Research Associate in the laboratory of Professor Ryan Morin at the Simon Fraser University, British Columbia, describes the development of novel droplet digital PCR assays for the detection and quantification of somatic mutations in B-cell non-Hodgkin lymphoma (NHLs) samples. Hear how the method is suitable for fresh tumor, FFPE and liquid biopsies and overcomes limitations in analytical sensitivity, cost, and scalability seen in current mutation detection options. The approach offers potential for the prognosis and therapeutic management in B-cell NHLs.