Advancing neurodegeneration research with single-cell and spatial multiomics
This illuminating webinar tackles the intricate pathologies of neurodegenerative diseases. By harnessing the power of single-cell and spatial technologies, we’ll explore how a multidimensional view of biology can lead to groundbreaking insights into Alzheimer’s and Parkinson’s diseases.
Key Takeaways:
- Transform your histological analysis: Learn how to enhance your understanding of plaques and tangles and their effects on the surrounding microenvironment using Visium Spatial products to integrate spatial gene expression and protein detection.
- Dissect cellular contributions: Deepen your insights into the role of disease-associated cells in pathogenesis. Find out how to identify cell-type differences, discover unique subtypes, and pinpoint novel biomarkers with Chromium Single Cell products.
- Discover cutting-edge research: Single nucleus RNA and ATAC-sequencing technologies are unraveling the molecular and cellular dynamics of neurodegeneration.
- Alzheimer’s disease focus: Recent studies utilizing multiomic approaches across millions of nuclei from hundreds of patients have revealed complex gene regulatory networks and disease-associated cell states. Learn how these insights correlate with cognitive resilience and vulnerability, shedding light on how various brain cell types—such as excitatory and inhibitory neurons and microglia—are impacted at different stages of Alzheimer’s.
- Parkinson’s disease insights: We’ll also explore findings from a study on Parkinson's that identified 13 distinct microglial subpopulations in postmortem substantia nigra tissues from PD donors. This research highlights their unique chromatin characteristics and their roles in the inflammatory processes underlying PD pathology.
This Webinar is for:
- Neuroscientists, molecular biologists, and genomic researchers seeking to deepen their understanding of neurodegenerative diseases.
- Clinicians and translational researchers focused on Alzheimer's, Parkinson's, and related dementias.
- Professionals in pharmaceutical and biotech industries exploring advanced therapeutic development.
- Academics and lab scientists interested in leveraging single-cell and spatial multiomic technologies for cutting-edge discoveries.
This session is ideal for anyone looking to enhance their research with innovative tools and insights into the cellular mechanisms driving disease progression.
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
Speakers
With a Ph.D. in molecular biology from the Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznań, Poland, Dr. Ciesielska has a rich background in scientific research. Transitioning into a commercial role, she became a field application specialist at Bio-Rad, where she played a pivotal role in driving the adoption of droplet digital PCR across the CEE region. Currently, they empower scientists in Southeast Europe, Central and Eastern Europe, and the Middle East to successfully integrate cutting-edge single-cell and spatial transcriptomics technologies into their research. With over a decade of experience collaborating with researchers, Dr. Ciesielska remains passionately committed to advancing scientific innovation and discovery.
Moderator
